Sicca Syndrome – Sjogren Syndrom
Sicca Syndrome (Sjogren syndrome) - is an autoimmune disorder in which the glands that produce tears and saliva are destroyed, causing dry mouth and dry eyes. This condition may also affect many different parts of the body, including the kidneys and lungs.
What is The Cause of Sicca Syndrome?
The exact cause of Sjögren’s syndrome is not known, there is growing scientific support for genetic (inherited) factors. The genetic background of Sjögren’s syndrome patients is an active area of research. The illness is sometimes found in other family members. It is also found more commonly in families that have members with other autoimmune illnesses, such as systemic lupus erythematosus, autoimmune thyroid disease, type I diabetes, etc. About 90% of patients with Sjögren’s syndrome are female.
Sicca Syndrome Treatment
The treatment for Sicca syndrome is unknown, however you can manage the dry eye and dry mouth associated with Sjogren’s syndrome by using eyedrops and drinking water more frequently. But some people may need prescription medications, or even surgery.
Sicca Syndrome Medication
Depending on your symptoms, your doctor may suggest:
- Increase production of saliva. Drugs such as pilocarpine (Salagen) and cevimeline (Evoxac) can increase the production of saliva, and sometimes tears. Side effects may include sweating, abdominal pain, flushing and increased urination.
- Address specific complications. If you develop arthritis symptoms, you may benefit from nonsteroidal anti-inflammatory drugs (NSAIDs) or other arthritis medications. Yeast infections in the mouth should be treated with antifungal medications.
- Treat system-wide symptoms. Hydroxychloroquine (Plaquenil), a drug designed to treat malaria, is often helpful in treating Sjogren’s syndrome. Drugs that suppress the immune system, such as methotrexate or cyclosporine, may also be prescribed.
To relieve dry eyes, consider undergoing a minor surgical procedure to seal the tear ducts that drain tears from your eyes (punctal occlusion). Collagen or silicone plugs are inserted into the ducts for a temporary closure. Collagen plugs eventually dissolve, but silicone plugs stay in place until they fall out or are removed. Alternatively, your doctor may use a laser to permanently seal your tear ducts.
Clinical Research Columbus Ohio
About Columbus Clinical Research
Columbus Clinical Research was founded by Dr. Samir Arora, a proven leader with more than 12 years of clinical research experience. We are an independent, multi-therapeutic outpatient clinical research center located in Columbus Ohio, giving thousands of citizens in Central Ohio an opportunity to participate in clinical trials and research.
CCR’s staff includes 7 study coordinators, a medical technologist/ phlebotomist, two dedicated recruiters & administrative personnel for regulatory preparation. There are three physicians onsite every day. Specialist’s for Allergy and Immunology, a Pulmonologist and Family Practice Physician are available as needed. The experience level of our coordinators ranges from one to 24 years, with an average of six years. Our principal investigator has 12 years of experience.