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Clostridium Difficile Clinical Trials in Columbus

C-Diff Study

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Clostridioides difficile (also known as C. diff) is a bacterium that can cause gastrointestinal symptoms ranging from diarrhea to life-threatening inflammation of the colon. Illnesses caused by C. diff are most common in older individuals being treated in hospitals or long-term care facilities. It’s estimated to cause almost half a million illnesses in the United States each year and about 1 in 5 patients who get C. diff will get it again.

Common Causes of C. diff

The symptoms of C. diff are fever, diarrhea, and abdominal pain. Serious complications of C. difficile colitis include dehydration, rupture of the colon, and spread of infection to the abdominal cavity or body. Severe infection is life-threatening.

How to Recognize C. diff

The most common cause of C. diff is treatment with antibiotics. Antibiotics are believed to suppress normal colonic bacteria that usually keep C. diff from multiplying and causing colitis. Most cases of C. diff occur in patients in the hospital, but the number of cases that occur among individuals not having been in or recently discharged from the hospital has greatly increased.

How to Enroll

If you are 50 years of age or older, have taken antibiotics recently or have been hospitalized recently, but have not been diagnosed with primary C difficile infection (CDI), you may be eligible for a new study or clinical trial to evaluate a new C. diff vaccine.

Participants may be compensated for their time and travel. To get started, find out if you qualify by calling us at 614-501-6164, or completing our online volunteer form.

What Our Clients say

  • This is a great way to make extra money and be involved in a research study that will help and benefit many people to come. I’ve really enjoyed myself with the program and with the staff.

    V. Ivory
  • "Thank you for your courtesy and kindness. I felt confident and comfortable. I would recommend the research study here. My coordinator was awesome and very caring."

  • Any stigma or hesitation about clinical research should be disregarded. A good learning program for research studies.

  • It's a good way to find out if there's some new drugs that can help people that have problems like mine and the people here are just wonderful to work with.


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